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Clinical proof

ZO protocols are builtto be measured.

ZO Skin Health supports comprehensive protocols across skin types, ages, and concerns with advanced formulation science and clinical study data behind key technologies.

Studies8-12 weeks
Technologies5 systems
PurposeMeasured care

Formulation science

Advanced ingredients,clearer expectations.

The clinical proof story is not just about individual products. It is about how ZO technologies support the bigger protocol: texture, barrier recovery, firmness, tone, and daily protection.

8

Weeks can be enough to document visible improvements in selected ZO studies.

5

Proprietary technology systems help support firmness, skin quality, hydration, and antioxidant defense.

ZO clinical proof product and skin science image

Proprietary technology

The complexes behindthe protocol.

ZO highlights five proprietary technologies across its clinical proof materials. They help explain why our in-office plans often pair treatment timing with specific at-home support.

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ZCORE®
Targeted firming complex

Improves the appearance of skin sagging, including neck skin.

Technology

ZCORE™ Complex

A firming-focused technology used to support visible skin tightening and the look of collagen and elastin structure.

ZPRO®
Biomimetic sericin protein complex

Minimizes the look of fine lines while enhancing skin plumpness and hydration from within.

Technology

ZPRO® Complex

Designed to support healthier-looking skin quality, complexion clarity, and collagen-supporting outcomes.

ZO-RRS²®
Redness-reducing plant stem cell complex

Helps neutralize aging free radicals while soothing visible redness.

Technology

ZO-RRS²® Complex

An antioxidant-focused system that supports barrier recovery and helps defend against future visible damage.

Study-backed products

Product proofpatients can understand.

These study highlights are the kind of evidence we translate into plain-language protocol guidance during appointments.

Hydrating Crème product study image

Hydrating Crème

Hydration

89% of patients showed significant improvement in skin hydration by week 4.

Redness

70% of patients showed significant improvement in the appearance of redness by week 8.

Texture + Smoothness

100% of patients showed significant improvement in texture and smoothness by week 8.

Itching

82% of patients reported diminished itching due to increased hydration by week 8.

Firming Serum product study image

Firming Serum

Elasticity

Firming Serum is clinically proven to visibly improve skin elasticity.

88% elasticity improvement was measured at 12 weeks.

Firmness

Firming Serum is clinically proven to improve the appearance of firmness.

97% of participants showed significant improvement in skin firmness by week 12.

Sagging

Firming Serum is clinically proven to improve the appearance of sagging skin.

93% of participants showed significant improvement in the appearance of both mid-face and jawline skin sagging by week 12.

Wrinkle + Texture Repair product study image

Wrinkle + Texture Repair

Hydration

Wrinkle + Texture Repair is clinically proven to improve the skin's ability to retain hydration.

Lines + Wrinkles

Wrinkle + Texture Repair is clinically proven to improve the appearance of lines and wrinkles.

98% of participants showed improvement in crow's feet and facial fine lines by week 12.

Texture

Wrinkle + Texture Repair is clinically proven to improve the appearance of smooth texture.

93% of participants showed improvement in skin texture by week 12.

What this means locally

Proof matters mostwhen it guides the plan.

Our Houston treatment plans use clinical evidence as a starting point, then adjust around skin sensitivity, pigment risk, downtime, season, and what you can realistically maintain at home.

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